British chemist who was awarded the 1982 Nobel Prize for Chemistry
for his investigations of the three-dimensional structure of viruses
and other particles that are combinations of nucleic acids and proteins,
and for the development of crystallographic electron microscopy.
He then accepted a research fellowship at Birkbeck College of the University of London, undertaking the study of the structure of tobacco mosaic virus and other viruses. Klug's discoveries were made in conjunction with his own development of the techniques of crystallographic electron microscopy, whereby series of electron micrographs, taken of two-dimensional crystals from different angles, can be combined to produce three-dimensional images of particles. His method has been widely used to study proteins and viruses.
In 1958 Klug became director of the Virus Structure Research Group
at Birkbeck. In 1962 (at the invitation of Francis Crick, who shared
a Nobel Prize that year) Klug returned to Cambridge as a staff member
of the Medical Research Council; in 1978 he was named joint head of
its division of structural studies. He was knighted in 1988.
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