American physicist. He worked on the Manhattan Project before beginning a career at the U.S. Naval Research Laboratory. There, with Herbert Hauptman , he concentrated his studies on crystalline matter. They were awarded the 1985 Nobel Prize in Chemistry for the development of a mathematical model known as the direct method. Devised in the 1950s and 60s, the innovation greatly improved methods for analyzing three-dimensional molecular structures.
Dr. Jerome Karle was born in Brooklyn, New York, on June 18, 1918.
He was born into a family in which there were generations of artistic
people, several of whom had careers in the fine and commercial arts.
A career in science was a most remote profession. Nevertheless, at an
early age, perhaps eight or nine, he was avidly reading popular accounts
of science, for example those of Sir James Jeans, and from that time
on, he expected to spend his life in scientific pursuits.
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