Palade performed many studies on the internal organization of such cell structures as mitochondria, chloroplasts, the Golgi apparatus, and others. His most important discovery was that microsomes, bodies formerly thought to be fragments of mitochondria, are actually parts of the endoplasmic reticulum (internal cellular transport system) and have a high ribonucleic acid (RNA) content. They were subsequently named ribosomes.
Palade became a naturalized citizen of the United States in 1952 and
in 1958 a professor of cytology at Rockefeller Institute, which he left
in 1972 to direct studies in cell biology at Yale University Medical
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